Open access
Aug 2026
On the Robustness of Biomolecular Systems to Perturbations in Translational Resources
It is shown that the constitutive circuit exhibits sensitivity to resource perturbations, and that redesigning it with negative autoregulatory feedback enhances the contraction rate and reduces the steady-state deviation bound, though at lower expression levels.
Akshay Kumar Jaiswal, Esha Singh, Abhilash Patel et al.
· bioRxiv · 0 citations