Ultra-Stable Linker Strategies in Antibody–Drug Conjugates: Balancing Plasma Stability with Controlled Cytotoxic Payload Release
Targeted drug delivery has emerged as a transformative approach in cancer therapy, allowing selective destruction of malignant cells while minimizing systemic toxicity. Antibody-drug conjugates (ADCs) and other targeted delivery systems rely heavily on chemical linkers that connect highly potent cytotoxic agents to tar...