Abhishek Kumar Gautam

Statistical optimization and physicochemical characterization of acitretin-loaded nanostructured lipid carriers for enhanced topical delivery and sustained drug release

Acitretin is a first-line retinoid for the management of psoriasis and other hyperkeratotic skin disorders; however, its therapeutic application is limited by poor aqueous solubility, inadequate skin retention, and dose-dependent systemic adverse effects following oral administration. The objective of the present study...