Absalom Zamorano Carrillo

Computational Prioritization of Megalin-Aminoglycoside Recognition and Gentamicin-Associated Cellular Stress Responses.

The experimental and computational findings support a sequential in silico-to-in vitro workflow in which cellular assays define a gentamicin-associated stress phenotype, while molecular modeling identifies megalin CR10 as a structurally plausible aminoglycoside-recognition region that may contribute to tissue uptake or...