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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Achim Temme

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Open access Sep 2026

Antibody-TLR3 agonist-conjugates program the tumor microenvironment and induce immune responses leading to tumor regression in experimental EGFRvIII-positive glioma.

Infiltration of immunosuppressive M2-programmed macrophages shapes the tumor microenvironment (TME) and is correlated with poor clinical prognosis in cancer. The combinatorial induction of immunogenic tumor cell death and programming the TME from immunosuppressive to inflammatory by employing dsRNA agonists for the end...

Alexander Hagstotz, Isabell Schau, Michael Seifert et al. · 0 citations

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