Open access
Sep 2026
A mitochondrial insertion directs substrate selection and engagement by the protein unfoldase ClpX.
The force-generating ATPases Associated with diverse cellular Activities (AAA+) ATPase domain of protein unfoldases is specified for many substrates and other functional partners through elaboration with accessory domains. Mitochondrial homologs of the unfoldase ClpX contain an insertion within the AAA+ domain that is...
Adam DeCosta, R. Barrick, J. Kardon
· Journal of Biological Chemis... · 0 citations