Sep 2026
Abstract A018: Cancer Associated Fibroblasts regulate Humoral Immunity and B Cell Education within Tertiary Lymphoid Structures
Pancreatic ductal adenocarcinoma (PDAC) has a 5-year survival rate of just 13%. Immune checkpoint blockade (ICB) has revolutionized cancer therapy, yet has shown limited efficacy in PDAC, benefiting fewer than 1% of patients to date. Contributing to this, the PDAC tumor microenvironment (TME) is desmoplastic and comp...
Braden T. Stevenson, C. Arora, Maya Sivagnanalingam et al.
· Cancer Research · 0 citations