Review
Open access
Sep 2026
To express or not to express HLA-G: tissue undifferentiation is the answer in gastrointestinal tumors.
Human leukocyte antigen G (HLA G) is a non-classical HLA class I molecule with, potent tolerogenic activity, mainly restricted to immune-privileged tissues under, physiological conditions. However, aberrant HLA G expression has been increasingly, reported in tumors, where it acts as an immune checkpoint contributing to...
Ignacio Juarez, Sandra Fernández-Uría, Christian Vaquero-Yuste et al.
· Human Immunology · 0 citations