Author

Aderson Vasconcelos Santos

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Review Open access Sep 2026

MODULATION OF CARBOHYDRATE DIGESTION BY PLANT-DERIVED INHIBITORS OF MGAM AND SI SUBUNITS: A STRUCTURED NARRATIVE REVIEW APPLIED TO THREE BRAZILIAN CERRADO SPECIES

Postprandial hyperglycemia is a well-established therapeutic target in diabetes mellitus, and the intestinal α-glucosidases maltase-glucoamylase (MGAM) and sucrase-isomaltase (SI) catalyze the terminal step of starch digestion. As approved inhibitors have limited uptake due to gastrointestinal adverse effects, there re...

L. Oliveira, João Bosco Ferreira de Souza, Dayara Soares Ruas et al. · Revista de Estudos Interdisc... · 0 citations

Open access Aug 2026

IN SILICO SCREENING OF NATURAL ERGOSTEROL PATHWAY INHIBITORS IN CANDIDA ALBICANS

The findings support the potential of these flavonoids as selective, low-toxicity SQLE inhibitor candidates and reinforce the value of in silico screening in guiding future in vitro and in vivo validation of novel antifungal therapies derived from plant biodiversity.

L. Oliveira, Agueda Maria de França Tavares, Aderson Vasconcelos Santos et al. · Revista de Estudos Interdisc... · 0 citations