Background: Human Immunodeficiency Virus (HIV) remains a major global public health challenge. According to the World Health Organization (WHO), in 2025, approximately 41 million people were living with HIV, with an estimated 570,000 deaths attributable to HIV-related causes and 1.2 million new HIV infections. These fi...
M. R. Hidayatullah, Adinda Nezma Meidina, Salwa Adilah Ningtiyas et al.· SCRIPTA SCORE Scientific Med...· 0 citations
Background: Human Immunodeficiency Virus (HIV) remains a major global health challenge with high morbidity and mortality rates. Although antiretroviral therapy (ART) effectively suppresses viral replication, it is unable to eradicate latent HIV reservoirs, preventing complete viral clearance. Advances in genome editing...
M. R. Hidayatullah, Salwa Adilah Ningtiyas, Adinda Nezma Meidina et al.· SCRIPTA SCORE Scientific Med...· 0 citations
The findings indicate that CRISPR-Cas9 can target multiple stages of the HIV life cycle, including disruption of viral entry coreceptors, inhibition of viral replication, and elimination of latent proviral DNA integrated within host genomes.
M. R. Hidayatullah, Salwa Adilah Ningtiyas, Adinda Nezma Meidina et al.· 0 citations
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