Author

Adithya V. Madduri

2 papers indexed here

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Preprint Aug 2026

Rare Diseases, Common Dilemmas: LLMs Prioritize Equal Resource Distribution over Patient Benefit in Decision-Making

This work presents a benchmark of 208 clinically grounded rare disease vignettes and identifies a strong authority-framing effect: models favor justice in committee-based contexts and shift toward beneficence and autonomy only when final decisions are framed as being made by clinicians or patients respectively.

Min-Da Zhao, Xuheng Han, R. Goel et al. · 0 citations

Review Open access Jul 2026

Learning Minimal Gene Programs for Disease-Aligned Representations

Identifying small, interpretable gene sets that robustly capture disease-associated variation in singlecell transcriptomic data remains a central challenge for biological interpretation and experimental followup. In practice, commonly used differential expression and sparsity-based approaches often produce large, unsta...

Adithya V. Madduri, Chirag J. Patel · bioRxiv · 0 citations