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Author

Adriana Coricello

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2 papers indexed here

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Open access Aug 2026

Identification of New Putative Autotaxin Inhibitors via Structure‐Based Virtual Screening and Evaluation of Their Antiproliferative Properties Against Ovarian and Breast Cancer Cells

A virtual screening study of an in‐house molecular database of an in‐house molecular database highlighted five putative ATX inhibitors, demonstrating preliminary phenotypic effects, inhibiting cell proliferation with IC50 values mostly in the low micromolar range.

Angelina Boccarelli, Adriana Coricello, F. Ambrosio et al. · 0 citations
Review Jul 2026

Bioisosteric Replacement of Carboxylic Acids in PPAR Agonists: A Mini Review.

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that regulate metabolic homeostasis and represent important therapeutic targets for conditions such as type 2 diabetes, dyslipidemia, and cardiovascular disease. While classical modulators often rely on carboxylic acid moieties to anchor receptor...

Adriana Coricello, A. De Simone, Giovanni Bottegoni · 0 citations

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