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Author

Adriana Kahn

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2 papers indexed here

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Open access Oct 2026

TP53 Genomic Alterations Including Targetable Y220C Mutation in Advanced Breast Cancer

TP53 Y220C is a rare genomic alteration (GA) with emerging targeted therapies. However, its prevalence in breast cancer remains undefined. We evaluated the prevalence of the Y220C alteration and association with other GAs. A total of 23,760 patients with advanced breast cancer were analyzed by hybrid ca...

N. Casasanta, Adriana M. Kahn, N. Fischbach et al. · 0 citations
Review Open access Aug 2026

Beyond a single disease: review of rare histological subtypes of triple-negative breast cancer with implications for prognosis and treatment

The clinicopathologic and molecular features of rare TNBC histologies are summarized and emerging therapeutic vulnerabilities are discussed and integrated with molecular profiling may enable more precise risk stratification and guide biomarker-driven treatment strategies.

M. Gouveia, R. Bonadio, R. Barroso-Sousa et al. · 1 citation · ⚡1

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