Open access
Oct 2026
Nuclear blebs are composed of variable chromatin states and display increased transcription initiation relative to elongation.
Nuclear blebs are herniations of the nucleus that occur in many human conditions including aging, heart disease, muscular dystrophy, and many cancers. Nuclear blebbing causes nuclear rupture and cellular dysfunction. However, understanding the formation, stability, and identification of nuclear blebs remains an ongoing...
M. Clark, Antonela Losada, Sonia Jahng et al.
· Biology Open · 1 citation