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Agata Malinowska

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Open access Jul 2026

Asparagine-Guided Regulation of Redox Status and Autophagy in Sugar-Starved Lupin (Lupinus spp.) Embryonic Axes—A Transcriptomic and Proteomic Approach

Asparagine links nitrogen status with redox stabilization, vacuolar catabolism, and autophagy-related dynamics in sugar-starved lupin embryonic axes, consistent with asparagine-dependent modulation of several autophagy-related processes rather than with an effect restricted to a single autophagic step.

Szymon Stefaniak, Karolina Wleklik, K. Nuc et al. · 0 citations
Open access Aug 2026

Are components of the histone gene expression machinery functionally repurposed in terminally differentiated cells?

It is shown that in muscle and neural cells that have ceased to replicate their chromatin and permanently exited the cell cycle, HLBs are dismantled and NPAT, FLASH and Lsm11 are detected in the cytoplasm, suggesting that in postmitotic cells, NPAT and U7 snRNP become repurposed for functions unrelated to generating hi...

Xiao-cui Yang, Anthony Desotell, Agata Malinowska et al. · 0 citations
Open access Aug 2026

TTC33 forms a complex with WDR61 and PHF5A to recruit factors relevant to genomic integrity

Using a combination of biochemical assays, structural modeling and molecular dynamics, it is shown that TTC33 directly recruits WDR61 and PHF5A to assemble into a trimeric core complex (TANC), which then forms distinct interactions with either UNG1/2 or SF3B–CCDC97.

R. Tomecki, Małgorzata Drabko, Małgorzata Siek et al. · 0 citations

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