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Author

Agnieszka Szopa

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Review Open access Sep 2026

Nobiletin as a Geroprotective Flavonoid: Mechanisms of Action, Therapeutic Potential, and Challenges of Bioavailability

Despite promising preclinical results across various models, the clinical translation of nobiletin is hindered by poor oral bioavailability, complex extraction, and limited human data, so novel delivery systems offer potential solutions to enhance its bioavailability.

Szymon Sip, Anna Gościniak, Niklas Hoede et al. · 0 citations
Open access Aug 2026

Lichen-derived elicitors (Evernia prunastri extract and usnic acid) enhance phenolic compound accumulation in agitated shoot cultures of Lychnis flos-cuculi

It is demonstrated that agitated shoot cultures represent a promising sustainable source of bioactive compounds for pharmaceutical and biotechnological applications and biotic elicitation with lichen-derived compounds effectively enhances the production of valuable phenolic metabolites in L. flos-cuculi in vitro cultur...

M. Kikowska, Kamil Daněk, E. Studzińska-Sroka et al. · 0 citations

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