Ahmed A. Hefny

Novel 1,4-Diazepane derivatives as amyloid-beta (Aβ) aggregation inhibitors

Introduction Alzheimer’s disease (AD) is characterized by the aggregation of amyloid-beta (Aβ) peptides, particularly Aβ42 and Aβ40, which contribute to neurotoxicity and disease progression. The development of novel small molecule inhibitors capable of preventing Aβ aggregation represents a promising therapeutic strat...