In silico drug repurposing to identify activators targeting SLC7A11/xCT for cardiotoxicity: Molecular docking, dynamics simulation, and ADMET analysis
Drug-induced cardiotoxicity remains a major challenge in pharmaceutical development, necessitating the identification of protective agents against cardiac damage. The cystine/glutamate antiporter solute carrier family 7 member 11/ cystine-glutamate antiporter (SLC7A11/xCT) plays a crucial role in cellular defense a...