Chronic musculoskeletal pain remains a leading cause of disability worldwide, driven by progressive degeneration of cartilage, bone, tendon, intervertebral discs, and peripheral nerves. Conventional interventional approaches primarily address symptoms without restoring structural integrity or tissue homeostasis. Regene...
Hamsa Priya Bhuchakra, Ahmed I. Anwar, Abdul-rahman A. Hegazi et al.· Biophysica· 0 citations
Pain pharmacology encompasses a complex relationship between neurobiological pathways, receptor systems, and pharmacologic agents that mediate or modulate pain perception and inflammation. In the context of the ongoing opioid crisis, understanding traditional and emerging approaches to pain management is critical. This...
Ahmed I. Anwar, Riley K. Noble, Kyle Jenks et al.· Psychopharmacology bulletin· 0 citations
Neurodegenerative diseases are targets for pridopidine therapy, which aims to improve quality of life through neuroprotective mechanisms that involve sigma-1 receptor (S1R) activation. Neurodegenerative motor and cognitive diseases are influenced by dopamine imbalance, where disruptions in pathways contribute to states...
Ahmed I. Anwar, Abdul-Rahman A. Hegazi, Hamsa Priya Bhuchakra et al.· Neurology International· 0 citations
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