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Author

Ahmed M. Fatouh

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Open access Sep 2026

Advanced hybrid-stabilized cinacalcet nanocrystals for enhanced oral bioavailability: formulation and integrated in vitro/in vivo evaluations

Introduction Cinacalcet (CINA), a Biopharmaceutics Classification System (BCS) Class IV drug, exhibits limited oral bioavailability due to poor aqueous solubility and low intestinal permeability. We aimed to mechanistically enhance the oral bioavailability of CINA through the development of advanced hybrid-stabilized n...

Rawan Gamal Eldin, Salma M. Mosleh, O. Saher et al. · 2 citations

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