Preclinical Evaluation of the SMNP-Adjuvanted R21 Malaria Vaccine Across Multiple Mouse Strains
Background: Adjuvants can enhance the immunogenicity of virus-like particle (VLP) vaccines. VLP-based malaria vaccines (RTS,S and R21) have demonstrated the potential of this approach and have now been deployed in many countries. However, the efficacy of these vaccines decays over time and could be improved by better v...