Author

Ahmed Sabt

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Open access Nov 2026

Design, Synthesis, and Biological Evaluation of Molecular Hybrids Incorporating Coumarin‐Pyrazole‐Linked Indolinone Derivatives With Antioxidant and Anti‐Alzheimer Properties

ABSTRACT The increase in global life expectancy has resulted in a significant rise in the occurrence of Alzheimer's disease (AD), making it a critical public health burden. Therefore, there is an urgent need to create effective methods to prevent or slow down the progression of the disease. In this regard, fifteen prev...

Ahmed Sabt, W. Aboulthana, Abdulrahman M. Saleh et al. · Chemistry and Biodiversity · 0 citations

Open access Aug 2026

Development of isonicotinoyl-azole hybrids as potential InhA inhibitors for anti-tubercular activity.

The development of innovative treatment medicines that can overcome drug resistance and intracellular persistence is necessary since tuberculosis (TB) continues to be a significant worldwide health burden. In this work, series of hybrid compounds containing azole moieties, imine/semicarbazide linkers, and isonicotinoyl...

Wagdy M. Eldehna, Zainab M. Elsayed, M. Korycka-Machała et al. · RSC Medicinal Chemistry · 0 citations

Open access Aug 2026

Development of new imidazopyridine-based chalcones hybrids as potent antidiabetic and antioxidant agents: synthesis, in silico and in vitro evaluation

A novel series of six imidazopyridine-based chalcone hybrids is synthesized and evaluated their in vitro biological activities, including total antioxidant capacity, iron-reducing power, and radical scavenging (DPPH, ABTS, NO), as well as antidiabetic potential against α-amylase, α-glucosidase, and aldose reductase.

Hanan Abdelmawgoud Atia, Aladdin M. Srour, Hanaa Farag et al. · Scientific Reports · 0 citations