Open access
Sep 2026
3D Spatial Interactomics Maps the Dynamics of NF-κB Multiprotein Signalosomes in Single Cells
NFκB signaling drives inflammatory responses by rapidly assembling membrane-proximal multiprotein supercomplexes, yet how these assemblies are organized in space and time within the 3D interior of a single cell has remained uncharacterized. We addressed this by profiling endogenous NFκB protein-protein interactions wit...
Nicholas Zhang, Collin Leese-Thompson, H. Ozuna et al.
· bioRxiv · 0 citations