Single-Cell Definition and Functional Validation of a CTSD-Associated Macrophage State in Colorectal Cancer
Background/Objectives: Tumor-associated macrophage heterogeneity may influence colorectal cancer (CRC) outcomes. We investigated a CTSD-associated macrophage program and its functional relevance. Methods: Single-cell GSE132465 data (23 tumor and 10 normal specimens), TCGA colorectal expression and survival data, and th...