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Ai-Guo Meng

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Open access Oct 2026

Single-Cell Definition and Functional Validation of a CTSD-Associated Macrophage State in Colorectal Cancer

Background/Objectives: Tumor-associated macrophage heterogeneity may influence colorectal cancer (CRC) outcomes. We investigated a CTSD-associated macrophage program and its functional relevance. Methods: Single-cell GSE132465 data (23 tumor and 10 normal specimens), TCGA colorectal expression and survival data, and th...

Zhao-Juan-Hui Wang, Bin Hou, Chun-Yan Liu et al. · 0 citations

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