Author

Ai-Jian Qin

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Open access Sep 2026

Development and Protective Evaluation of an O18–CRM197 Glycoconjugate Candidate Preparation Against APEC O18 Challenge in SPF Chickens

Avian pathogenic Escherichia coli (APEC) is an important cause of colibacillosis in poultry, and increasing antimicrobial resistance has highlighted the need for alternative preventive strategies. This study aimed to develop an O18-cross-reacting material 197 (O18–CRM197) glycoconjugate vaccine candidate using an Esche...

Ting-Fan Zhu, Jing Yuan, Kang-Mei Feng et al. · Microorganisms · 0 citations

Open access Sep 2026

Novel emerging reassortant H6 avian influenza viruses with internal genes from G57 genotype of H9N2 pose potential zoonotic risk

ABSTRACT In recent decades, multiple novel reassortant avian influenza viruses (AIVs) carrying internal genes derived from H9N2 viruses have emerged in poultry in China and have repeatedly caused human infections, highlighting the pivotal role of the H9N2 internal genes cassette in facilitating cross-species transmissi...

Zhi-Min Wan, Wenjie Jiang, Xu-Dong Cao et al. · Emerging Microbes and Infect... · 0 citations

Open access Aug 2026

D347G in PA is critical for the pathogenicity of H9N2 avian influenza A virus in mice

It is demonstrated that a novel molecular marker, D347G in PA, determines the virulence of H9N2 in mice, posing a potential risk of H9N2 with D347G in PA for public health and highlighting the significance of continuing surveillance of H9N2 field strains.

Zhe-Hong Zhao, Ye Tian, Wenjie Jiang et al. · Virulence · 1 citation