Author

Ai-Ming Yu

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Review Open access Aug 2026

Targeting Immune Checkpoint Proteins in Cancer Therapy and the Potential of RNAi-Based Immunotherapy

Preclinical and early clinical studies have indicated effective downregulation of target ICP expression and enhanced antitumor immunity across diverse cancer models, underscoring the potential of RNAi-based immune checkpoint modulation, complementing existing ICIs and expanding the next generation of cancer immunothera...

Katherine K. Wang, Ai-Ming Yu · Pharmaceuticals · 0 citations

Open access Jul 2026

Efficacy of Bioengineered PD-L1 siRNA for Immunotherapy Against Non-Small Cell Lung Cancer Cells

The potential of bioengineered PD-L1 siRNA entities for NSCLC immunotherapy is demonstrated and their immunotherapeutic efficacy against non-small cell lung cancer (NSCLC) in vitro is defined.

N. Batra, Mei-Juan Tu, Su Guan et al. · Non-Coding RNA · 0 citations