Rational design of a dual-function, LL-37/HNP-1, chimeric antimicrobial peptide: a broad-spectrum AMP against respiratory co-infections
Respiratory viral–bacterial co-infections remain difficult to treat because current therapies typically target pathogens individually. In this study, we designed and computationally evaluated a dual-function chimeric antimicrobial peptide that integrates the conserved antiviral and antibacterial domains of LL-37 and hu...