Synthesis and characterization of selected new thiazolidine-2,4-diones derivatives: SwissADME and density-functional-theory analysis
The synthesis of novel thiazolidine-2,4-dione derivatives, their pharmacokinetic profile, and their structural features for drug-like potential are all covered in the current work. Thiazolidine-2,4-dione was selected as a core scaffold due to its well-established role as a privileged pharmacophore in antidiabetic drug...