Secreted phosphoprotein 1 (SPP1, also known as osteopontin, OPN) is a multifunctional matricellular glycoprotein that is aberrantly overexpressed in nearly all major human malignancies. It functions as a central signaling hub that drives tumor initiation, sustains cancer stemness, accelerates invasion and metastasis, r...
Yu Xia, Dong Han, Song-Xia Tang et al.· International Journal of Onc...· 0 citations
A protocol for integrating RNA hybridization with in situ tagmentation using chromatin isolation by RNA purification-tag (ChIRP-Tag) is presented, which captures RNA-associated chromatin with high sensitivity and spatial resolution across various cell types.
Ruishuang Fu, Rongjie Zhao, Huimin Yang et al.· STAR Protocols· 0 citations
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