Environmental enrichment differentially suppresses anxiety-related behaviors, reduces passive avoidance learning, and upregulates hippocampal brain-derived neurotrophic factor expression in high- and low-avoidance Hatano rats.
Anxiety disorder risk is influenced by both adverse environmental factors and genetic background. We previously described high-avoidance animal (HAA) and low-avoidance animal (LAA) strains of male Hatano rats that may provide robust models for assessing interactions between genetic background and environment driving an...