Tumor hypoxia is a hallmark of solid tumors that promotes aggressiveness and resistance to therapy. Within hypoxic tumors, hypoxia-inducible factor (HIF)-dependent transcriptional programs drive metabolic reprogramming, lactate accumulation, extracellular acidosis, angiogenesis, immune suppression, and invasive phenoty...
S. Askarova, Sanazar Kadyr, Aislu Yermekova et al.· Oxygen· 0 citations
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