Author

Aiym Kaiyrlykyzy

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Open access Oct 2026

Gut Microbiome Alterations in Alzheimer’s Disease: A Shotgun Metagenomic Case–Control Study

AD in this Central Asian cohort was associated with a less diverse, compositionally distinct gut microbiome, with depletion of butyrate-producing Firmicutes and enrichment of sulfate-reducing taxa, alongside other taxa whose direction of association differed from prior reports.

A. Issilbayeva, S. Kozhakhmetov, A. Kushugulova et al. · International Journal of Mol... · 0 citations

Open access Oct 2026

Genome-Wide Genotype Resource and Exploratory Association Analysis of Alzheimer’s Disease in a Kazakh Population: A Case–Control Study

Background/Objectives: Alzheimer’s disease (AD) has a substantial genetic component, yet Central Asian populations remain markedly underrepresented in genomic studies of the disease. Methods: to address this gap, we generated array-based genotype data using an immune-focused genotyping platform from a Kazakh AD case–co...

Aiym Kaiyrlykyzy, Aygerim Serikzhan, A. Kassenova et al. · Biomedicines · 0 citations