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Author

Aizhen Guo

2 papers indexed here

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Open access Aug 2026

Carboxypeptidase A6 contributes to bovine enterovirus F production through apoptosis-associated PI3K/AKT/FOXO1 signaling

ABSTRACT Bovine enterovirus (BEV), a member of the family Picornaviridae, is an understudied pathogen associated with bovine enteric and respiratory disease, and host factors supporting its infection remain poorly defined. Here, a genome-wide CRISPR/Cas9 loss-of-function screen in Madin–Darby bovine kidney cells identi...

Yuanchen Geng, Hao Yang, Qimeng Wu et al. · 0 citations
Jul 2026

The AAA+ chaperone ClpB contributes to stress tolerance and pathogenesis in Mycoplasma bovis.

ClpB, an ATP-dependent molecular chaperone belonging to the Hsp100/Clp subfamily of AAA+ ATPases, plays a crucial role in protein disaggregation, thereby enhancing bacterial survival under stress conditions. Despite its well-conserved function in prokaryotes, the specific contributions of ClpB to the pathogenesis of th...

Hui Zhang, Doukun Lu, Gang Zhao et al. · 0 citations

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