Open access
Jul 2026
Acute rapamycin treatment reveals distinct mechanisms of dysfunction in a maternal inflammation mouse model
Maternal inflammatory response (MIR) during early mouse gestation induces a cascade of physiological and behavioral changes associated with autism spectrum disorder (ASD). We have shown that mild MIR causes chronic systemic and brain inflammation, mTOR pathway activation, mild brain overgrowth with regionally specific...
Janel Le Belle, M. Condro, C. Cepeda et al.
· Nature Communications · 0 citations