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Author

Ajit Kumar

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Sep 2026

Exploring the Potential of Quinoline-Containing Pyrazoline Derivatives as Antidepressant Agents: In Vivo and In Silico Studies.

INTRODUCTION/OBJECTIVE Depression is a common mental disorder, affecting over 300 million people worldwide. Currently available treatments, such as SSRIs, SNRIs, TCAs, and MAOIs, have limited effectiveness and cause side effects. The pharmacological potential of compounds based on diverse novel heterocyclic scaffolds,...

B. Sharma, Chahat, Pawan Kumar et al. · 0 citations
Aug 2026

In silico investigation of novel isatin derivatives as potential multi-target anticancer agents targeting VEGFR-2, EGFR, and caspase-6.

This study highlights the usefulness of computational approaches in the discovery of novel isatin-based multi-target lead candidates for cancer therapy and suggests that compound 4 represents a promising lead for further investigation.

Vipul Kumar, Vivek Kumar, P. C. Sharma et al. · 0 citations

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