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Akhil Patel

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Open access Sep 2026

Design of bifunctional pyridinophane ligands as Mn2+ MRI agents for diagnostic imaging of Alzheimer's disease

The diazapyridinophane scaffold is established as a viable first-generation platform for blood–brain barrier (BBB)–permeable Mn2+ MRI contrast agents and both the bifunctional chelators and their Mn2+ complexes exhibit appreciable affinity for Aβ aggregates.

T. El Sayed, Akhil Patel, Ke-Rui Xu et al. · 0 citations

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