Conserved structural dynamics of MTHFR2 link one-carbon metabolism to metabolite-based plant immunity.
Methylenetetrahydrofolate reductase 2 (MTHFR2) plays a vital role in the one-carbon (1C) pathway, mediating plant immunity in Arabidopsis against rice blast, a role conserved across the plant kingdom. To understand the structural, conformational dynamics, evolutionary modifications and molecular activity of MTHFR2, we...