Open access
Aug 2026
Engineering a Highly meta -Selective Biphenyl Monooxygenase for the Biosynthesis of High-Value Polymer Precursors
The meta-selective C–H functionalization of aromatic substrates lacking meta-directing electron-withdrawing groups remains challenging. To engineer the regioselective enzymatic conversion of biphenyl (BP) to 3,3′-dihydroxybiphenyl (33DHBP), an industrial precursor to high-performance polymers, substrate positioning w...
C. Vavricka, Takeshi Matsui, Satoshi Yuzawa et al.
· ACS Catalysis · 0 citations