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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Akihito Harada

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2 papers indexed here

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Open access Sep 2026

Cryo-EM structures of CENP-A nucleosomes isolated from human cells

Centromeres ensure accurate chromosome segregation, and their identity is specified epigenetically by the histone H3 variant CENP-A. Although the structures of reconstituted CENP-A nucleosomes have provided important insights, how this epigenetic mark is structurally organized within native chromatin remains incomplete...

Eisho Tanida, Suguru Hatazawa, Takumi Oishi et al. · 0 citations
Open access Aug 2026

SOX2 terminates trophectoderm competence in inner cell mass by closing trophectoderm enhancers

During embryonic development, cellular competence to respond to differentiation signals changes dynamically. Although the mechanisms underlying competence acquisition have been extensively studied, those underlying competence loss remain unclear. In preimplantation mouse embryos, Hippo signaling shifts from regulating...

Naoki Hirono, M. Uchikawa, Arisa Tanigawa et al. · 0 citations

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