Author

Ala Jo

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Open access Aug 2026

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally invasive biomarkers that report tumor development at earlier stages. Extracellular vesicles (EVs) are promising analytical targets because they carry molecular cargo from their originating cells, b...

Mi Hyeon Cho, Yein Chung, Yoonjeong Choi et al. · Advancement of science · 0 citations

Aug 2026

Post-translational chemical modification of E3 ligase for efficient target protein degradation.

This work reports the first ligand-directed chemical strategy that converts transient PROTAC-mediated ternary complex formation into binary target recognition via post-translational chemical modification of an E3 ligase, and believes it could provide a platform for next-generation targeted protein degraders to overcome...

Eunbin Park, Jinjoo Jung, G. J. Kumar et al. · Bioorganic chemistry (Print) · 0 citations