Alaa H. Fadel

In silico study of thiazole-based amino coumarin derivatives with promising carbonic anhydrase inhibitory activity.

OBJECTIVE Aim: In this study, a series of novel aminocoumarin derivatives incorporating an amino-thiazole moiety were designed to evaluate their inhibitory activity against the carbonic anhydrase IX enzyme (PDB ID: 6fe0) and to explore their potential anti-neoplastic properties through molecular docking analysis. PAT...