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Author

Alan J. Davidson

2 papers indexed here

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Open access Sep 2026

Large-scale organoid-derived cyst cultures as a drug discovery platform for polycystic kidney disease.

INTRODUCTION Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the slow, progressive formation of fluid-filled cysts within the kidneys, ultimately leading to kidney failure. Despite being the most common genetic kidney disease, therapies for ADPKD are limited. Ureteric bud (UB) organoids derived...

T. Vanichapol, Ruby Wangford, Shyla Mishra et al. · 0 citations
Open access Jul 2026

Morula complementation restores fetal kidneys in xenocompatible SALL1 null sheep

Fetal kidney development was anatomically and histologically restored in sex-chimaeric hosts, providing proof-of- concept for using sheep as a new model species for in vivo organ generation.

S. J. Appleby, Lisanne M. Fermin, S. Delaney et al. · 0 citations

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