Alan Lai

Metabotropic Glutamatergic Signaling Adaptively Controls Trans-thalamic Communication

Trans-thalamic circuits link cortical regions through higher-order sensory (HOs) thalamic nuclei to support cognition. These circuits are rich with metabotropic glutamate receptors (mGluRs), whose seconds-long dynamics conflict with the thalamus’s traditional relay role, leaving their function unknown. Here, we present...