Open access
Aug 2026
Endolysosomal remodeling and acidity dictates ferroptosis sensitivity to iron oxide nanoparticles.
It is demonstrated that lysosomal acidity and plasticity critically regulate iron mobilization, ROS compartmentalization, and the ferroptotic response triggered by dimercaptosuccinic acid-coated IONPs in MDA‑MB‑231 breast cancer and U87MG glioma cells.
Neus Daviu, Alberto Irigaray-Moreno, Carla Graciano-Casero et al.
· Biomedicine & pharmacotherap... · 0 citations