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Author

Alberto Paccanaro

Royal Holloway University of London

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#artificial intelligence Preprint Sep 2026

Hyperbolic Graph Representation Learning for Differential Diagnosis on Biomedical Knowledge Graphs

A preliminary study of hyperbolic graph representation learning for Mendelian-disease differential diagnosis on a patient-integrated biomedical graph suggests that hyperbolic embeddings can exploit biomedical hierarchical structure while supporting diagnostic reasoning over heterogeneous patient-level graphs.

Pietro Miotto, Lucia Mellini, Tommaso Marzi et al. · 0 citations
Open access Aug 2026

A linear interpretable model for drug target prediction

The results indicate that simple linear models with well-curated similarity features can deliver robust and interpretable DTI predictions, facilitating hypothesis generation and downstream experimental prioritization.

Santiago Noto, Santiago Ferreyra, Rubén Jiménez et al. · 0 citations

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