Aleema Iqbal

179 Characterisation of tumour-directed B cell responses in glioblastoma through single-cell transcriptomics and serological profiling

Glioblastoma (GBM) is the most common and aggressive primary brain tumour in adults, with a median survival of approximately 15 months despite multimodal treatment. The GBM tumour microenvironment is recognised as profoundly immunosuppressive, yet the role of B cell-mediated humoral immunity remains largely unexp...