Molecular overlap between primary immune thrombocytopenia and inherited platelet disorders: A pediatric case report with a novel heterozygous ITGB3 variant identified by next-generation sequencing
Primary immune thrombocytopenia (ITP) in children is typically self-limited. However, persistent and treatment-resistant cases require evaluation of alternative pathogenic mechanisms. We report a 12-year-old female with persistent ITP unresponsive to corticosteroids and intravenous immunoglobulin, in whom genetic tes...