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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Alem W. Kahsai

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2 papers indexed here

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Review Sep 2026

Bias from within: intracellular allosterism and the ICL2 hub.

Targeting the orthosteric site of G protein-coupled receptors (GPCRs) has long dominated drug discovery, but intracellular allosteric modulators (AMs) provide new avenues to enhance selectivity and fine-tune signaling. Recent structural advances have illuminated intracellular allosteric pockets that act as conformation...

Yang Zhou, Alan Long, Joshua D. Gross et al. · 0 citations
Open access Jul 2026

Conformational Basis of Functionally Selective Allosteric Modulation of the Angiotensin II type 1 Receptor by Small Molecules

The DNA- encoded library screening-guided isolation and pharmacological characterization of the first small molecule AT1R allosteric ligands are reported, uncovering new mechanisms for precisely controlling the dynamic behavior of the AT1R with implications for drug development targeting this pathophysiologically impor...

Samuel Liu, Peng Xiao, M. Elgeti et al. · 0 citations

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