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Author

Alessandra Cavegn

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2 papers indexed here

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Open access Oct 2026

Steric Stabilization of Lipid Nanoparticles by Sequence-Defined Polymer−Lipids Enhances Gene Expression

Polyethylene glycol (PEG) conjugated lipids are frequently used for the design of lipid nanoparticles (LNPs) in the field of gene therapy. However, conventional PEG−lipids contain a distribution of polymer chain lengths. To overcome this limitation, we have prepared a structurally defined PEG-alternative polymer-lipi...

E. Ü. Kuzucu, Alireza Kavand, Arséne Timothée Tergalinsky et al. · 0 citations
Open access Aug 2026

Enhanced nuclear import of DNA-lipid nanoparticles by peptide co-encapsulation.

It is demonstrated that LNPs can be combined with NLS peptides to promote non-viral DNA delivery to the nucleus by endogenous nuclear import pathways.

Alessandra Cavegn, Kevin N. Baumann, David Wang et al. · 0 citations

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