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Author

Alessandra Esposito

2 papers indexed here

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Review Open access Aug 2026

Pan-tumor spatial transcriptomics reveals conserved properties of tumor organization

Summary Tumor microenvironments (TMEs) are compositionally and functionally heterogeneous, making it challenging to discover organizing structural principles. Through a study of 262 solid tumors profiled by spatial transcriptomics, we identify a conserved architecture where TMEs are partitioned into discrete, hierarchi...

Vivek Behera, Alexander Guzzetta, Hannah Giba et al. · 0 citations
#artificial intelligence Open access Sep 2026

Clinical usability of an explainable AI decision support tool and evaluation of multimodal models in NSCLC.

Despite a decade in, immunotherapy (IO) treatment selection in non-small cell lung cancer (NSCLC) remains largely guided by subgroup analyses and imperfect programmed death ligand 1 (PD-L1) and clinical scores. To our knowledge, I3LUNG ( NCT05537922 ) is currently the largest international, real-world, multimodal, arti...

A. Prelaj, V. Mišković, Matteo Sacco et al. · 0 citations

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